Eric Selker, Mentor
Biology
Francis Maddox, McNair
Scholar
Professor Eric Selker received his Ph.D. from Stanford University
in 1980 and joined the UO faculty in 1985. His lab, part of the
Institute of Molecular Biology, focuses on DNA methylation and chromatin
modifications. Core research in the lab focuses on "how the eukaryotic
genome is structured, how it functions, and how it changes. Our
current research is focused on gene silencing in eukaryotes. We
are particularly interested in mechanisms involving special states
of chromatin (e.g. heterochromatin)and DNA methylation." Recent
publications include "Controlling DNA Methylation: Many Roads to
One Modification," Current Opinion in Genetics and Development (2005);
and "In Vitro and In Vivo Analyses of a phe/tyr Switch Controlling
Product Specificity of Histone Lysine Methyltransferases," Journal
of Biology and Chemistry (2005).
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